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Characteristics, Risk Factors and Prevention of HIV Polyneuropathy in South Africa (HIV Neuropathy)

About the Study

Principal Investigator: Jeannine Heckmann, MD, PhD
Site-PIs: Taylor Harrison, MD and Michael Benatar, MD, PhD

Patient Medical History FormHIV and Tuberculosis are endemic in South Africa.  An epidemic of HIV-associated neuropathy is anticipated in the context of use of stavudine-containing anti-retroviral regimens. Our preliminary goals are to investigate risk factors for HIV neuropathy such as concurrent tuberculosis infection, prior or ongoing anti-TB therapy and nutritional deficiency.

Eligibility Criteria
  • HIV positive
  • Anti-retroviral drug naive
  • Age > 18 years
Funding Agencies

Emory Univ

Emory Global Health Institute, Emory University Research Committee

Collaborators
  • Jeannine Heckman, MD, PhD
  • Taylor Harrison, MD
  • Joel Dave, MD
Contact

Site-PI

  • Michael Benatar, MD, PhD

Contact Information

  • Email: mbenatar@med.miami.edu
Links
Publications
  • Centner CM, Carrara H, Harrison TB, et al. Sensory polyneuropathy in human immunodeficiency virus-infected patients receiving tuberculosis treatment. Int J Tuberc Lung Dis. 2014 Jan;18(1):27-33. [ PubMed Link ]
  • van der Watt JJ, Harrison TB, Benatar M, Heckmann JM. Polyneuropathy, anti-tuberculosis treatment and the role of pyridoxine in the HIV/AIDS era: a systematic review. Int J Tuberc Lung Dis. 2011 Jun;15(6):722-8. [ PubMed Link ]
  • Maritz J, Benatar M, Dave JA, et al. HIV neuropathy in South Africans: frequency, characteristics, and risk factors. Muscle Nerve. 2010 May;41(5):599-606. [ PubMed Link ]
Presentations and Lectures

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Contact Us

By phone:
For familial ALS and general inquiries:
1-888-413-9315
For the CReATe Consortium and related studies:
1-844-837-1031

By email:
fals@miami.edu (For familial ALS inquiries)
projectcreate@miami.edu (For CReATe inquiries)
alsresearch@miami.edu (General inquiries)

Support Our Research

Affiliates

  • CReATe Consortium
  • CReATe Connect
  • The Kessenich Family ALS Center at UM
  • ALS Recovery Fund
  • ALS Association
  • Muscular Dystrophy Association
  • CDC National ALS Registry
  • The Northeastern ALS Consortium
  • Myasthenia Gravis Research Group
Read Our Newsletter

News

  • Biomarker for ALS Disease Progression Identified by the Teams at University of Miami and Flinders University!03/07/2017 - 5:48 pm
  • Brain MedicineDr. Benatar presents promising phase II trial results of Arimoclomol in SOD1 ALS12/09/2016 - 5:02 pm
  • CReATe Consortium Virtual Journal Club12/08/2016 - 3:18 pm
More News
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